Mixing substances can result in serious health problems including damage to the brain, heart and liver, seizures, heart attack, and stroke.

Mixing stimulants (like ADHD medication) and depressants (alcohol or cannabis) is dangerous because the results are unpredictable. The effects don’t cancel each other out.

Mixing alcohol and cannabis (both depressants) together can result in severe intoxication and impairment, because alcohol increases THC absorption.